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In published preclinical and older clinical research, DSIP has been administered across a wide range of doses and routes, reflecting the molecule's exploratory history rather than any settled protocol (PMID 6145137, PMID 3550726, PMID 1299794)
Over time, researchers noticed that levels of GHK-Cu tend to decrease with age, which led to further interest in how it relates to skin appearance
PMC 4145307
During follow-up visits, healthcare providers typically consider the patients overall health, treatment goals, symptom changes, lifestyle habits, and clinical response rather than relying on a single measurement or photograph
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