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Early studies can identify common adverse events, but larger and longer studies help clarify less common risks, discontinuation patterns, and which groups may need extra caution

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Additionally, a 2021 investigation showed that Metformin may help protect against macular degeneration in older adults, while a 2022 study suggested that Metformin may reduce the need for joint replacement

(They think its because bipolar disorder looks so different in different people, while schizophrenia is more similar.) Why It Matters Bipolar disorder is challenging to diagnose, taking an average of seven years after symptoms start before its correctly diagnosed, per Michigan Medicine