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It can be caused by not getting enough of this vitamin through your diet, problems with absorbing it, or taking a medication that interferes with its absorption
According to USDA Agricultural Research Service data based on NHANES, approximately 6% of adults aged 60 and older in the United States are vitamin B12 deficient, defined as plasma B12 below 148 pmol/L (2009)
The study authors found that intravenous injection of 42mg to 1260mg of TB4 was safe in healthy adults, with no dose limiting toxicities or serious adverse events reported [26]
There is no published pharmacokinetic data confirming sublingual absorption produces systemic ERR agonism comparable to IP injection
