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Of the incident reports involving semaglutide, about 3,000 were linked to Wegovy and originated in six countries across three continents, and almost 21,000 were attributed to Ozempic, with reports from 11 countries across four continents

Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimers disease mouse model

It stimulates insulin release, slows gastric emptying and signals fullness to the brain

The DPP-4 inhibitor CV safety outcome trials have unequivocally demonstrated that DPP-4 inhibition is not associated with any increased risk of major adverse CV events (MACE), with the four trials so far published (124127) having hazard ratios (HR) for the primary outcome of between 0.96 and 1.02 (Table 2)