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The discovery that the G2019S mutation results in a constitutive two- to threefold increase in LRRK2 kinase activity [141, 142], along with evidence that LRRK2 mutations are risk factors for the more common sporadic form of PD [143, 144], prompted extensive investigation into its functional role
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doi: 10.1038/srep26859 88 GersteinHCHartRColhounHMDiazRLakshmananMBotrosFTet al
Glutathione IV drips are generally safe when administered by trained professionals
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