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BPC-157, which stands for Body Protection Compound 157, is a synthetic peptide

2 Since it is non-peptide, orforglipron avoids GI degradation barriers that limit peptides, thereby enabling once-daily administration while maintaining efficacy on glucose control, body weight, and tolerability

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Clinical evidence from the STEP 4 trial found that participants who continued weekly semaglutide injections for up to 104 weeks (2 years) maintained significantly more weight loss compared to those who stopped treatment after initial success