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Figure from Rossing et al NDT 2023 Primary Outcome This was a composite of time of first occurrence of: Onset of kidney failure (persistent eGFR 28 days or initiation of long-term KRT, kidney transplantation) Persistent 50% reduction in eGFR from baseline Death from kidney or CV causes Secondary Outcomes Confirmatory secondary outcomes were analyzed hierarchically

At Southern Care Anesthetics, we do not recommend or prescribe BPC-157, as its use falls outside current regulatory guidelines and established standards of care in anesthesiology and pain management

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Across remaining preclinical and animal studies, risk of bias was generally moderate, driven by small sample sizes, lack of explicit randomization or blinding, and indirectness to human metabolic outcomes