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These reactions can occur after the first or subsequent doses and may present as severe allergic responses, including difficulty breathing, swelling, and potentially life-threatening shock Khatrawi2022Sajan2023Ullah2018

XENical in the Prevention of Diabetes in Obese Subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients

Users do not report bloating or edema

Cagrilintide is a 39amino-acid peptide with structural modifications (including an N-terminal fatty diacid chain) designed to improve stability and reduce fibril formation compared with native amylin