In an insulin-resistant milieu, insulin may competitively inhibit IDE, which impedes the degradation of A proteins, increases their neurotoxicity, and contributes to the onset of AD (Scherer et al., 2021
But the best outcomes come from pairing the medication with: A plan you can actually follow A strategy for side effects A maintenance plan for the long haul And a serious commitment to protecting muscle with protein and strength training If youre thinking about starting, the most important question is not Which drug is best? Its: What is the safest plan that I can sustain, and how are we supporting my future self? References (APA) Aronne, L
Evans, PhD, and Steven Cummings, MD warn that sarcopenia in older adults may be especially concerning, as it can contribute to hip fractures, disability, and increased mortality
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