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In line with previous reports 11 and above in vivo findings, we found that TMCA treatment could inhibit the mRNA expression of Shp , an FXR downstream target, and increase the mRNA levels of Gcg and GLP-1 secretion in the STC-1 cells, NCI-H716 cells, and mouse intestinal organoids (Fig

Modifying the delicate balance of ROS in cancer cells is an attractive method for triggering selective cell death through various pathways, such as ferroptosis, apoptosis, necroptosis, pyroptosis, parthanatos, oxeiptosis, and paraptosis

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