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While GLP-1 therapies can help reduce appetite and improve metabolic control, they are most effective when combined with healthy eating, regular physical activity, and ongoing behavioral support

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Ozempic , primarily for managing type 2 diabetes, also starts at 0.25 mg weekly for the first 4 weeks

One of the most promising interventions is dietary restriction (DR) of either calories in general or specific macronutrients, as it consistently has been shown to prolong life- and healthspan in a broad range of model organisms and possibly humans, too, when compared with unrestricted food intake