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This included a reduction in RAGE protein expression, suppression of key inflammatory cytokines (IL-6, IL-12, TNF-), and attenuation of matrix-degrading enzymes [9]

A structured approach can simplify this decision-making process: Assess cardiovascular and renal status : Patients with heart failure or kidney disease often benefit from SGLT2 inhibitors first

But no drug is without its risks, and we should definitely be keeping a close eye on how these groups will fare on GLP-1s over the long term

Because symptoms can overlap with neuromuscular and endocrine conditions, diagnosis should focus on the whole clinical picture rather than one lab value alone