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In this context, it has been demonstrated that treatments with either a GLP1/Estrogen (GLP1/E) conjugate, a unimolecular GLP1/GIP (gastric inhibitory peptide) dual agonist, or a GLP1/GIP/Glucagon triagonist, markedly reduced body weight and improved diabetic complications, including hyperinsulinemia, in preclinical models of obesity in males 33,34,35
Rare but serious side effects include pancreatitis and kidney or gallbladder problems
Checa-RojasADelgadillo-SilvaLFVelasco-HerreraMDCAndrade-DominguezAGilJSantillanOet al
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