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Acetyl-L-carnitine supplementation to old rats partially reverts the age-related mitochondrial decay of soleus muscle by activating peroxisome proliferator-activated receptor gamma coactivator-1alpha-dependent mitochondrial biogenesis
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Disruptions or impairments in mitochondrial network connectivity can lead to detrimental effects on cellular physiology and contribute to the pathogenesis of T21
Additionally, the by-product of H 2 O 2 activates the Erk1/2, which in turn, leads to cell proliferation in human breast cancer via involving estrogenic metabolism
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