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PPAR site-directed mutagenesis A pEF-BOS plasmid containing murine Ppara gene, as described in a previous literature 43 , was utilized to generate PPAR mutant constructs
Generally, the selection of a GLP-1 RA should involve consideration of available evidence in conjunction with relevant patient-specific factors such as CV risk, cost, and patient adherence
Tirzepatide: SURMOUNT-MMO At time of publication, the SURMOUNT-MMO trial evaluating tirzepatides cardiovascular outcomes in a similar population is ongoing
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