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LDLR promotes autophagy-mediated cisplatin resistance in ovarian cancer associated with the PI3K/AKT/mTOR signaling pathway

Biomaterials 144 , 119129 (2017)

Research protocols investigating long-term melanocortin signaling typically employ pulsatile dosing schedules (e.g., 1mg every 4872 hours instead of daily) to allow receptor resensitization between administrations

Rescue therapy was needed by 8%, 25%, and 67%, respectively. Five milligrams preserved most, but not all, of the benefit of continuing the effective dose

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