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In addition, efficacy in lowering glucose levels of SGLT2 inhibitors depends in the filtration rate in the kidneys, so it has shown no efficacy in reducing HbA1c levels in patients with severe renal impairment, ESRD and patients on dialysis, as well as some moderate renal impairment [28]
Journal of Clinical Endocrinology & Metabolism, 91(3), 799-805
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Promise and pitfalls Other scientists in the field are encouraged by the potential to target a new mechanism
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