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Under high glucose conditions Ex-4 was able to reverse glucose-induced suppression of proliferation in human Periodontal ligament stem cells (PDLSC) [17] and reduced cellular senescence in hMSC as confirmed by EdU staining, flow cytometry and cell cycle analysis [18]

Niedzwiecki, M

This is the second receptor engaged by Tirzepatide (the "twincretin" target)

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