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Gene-level modulation: Pickart & Margolina 2018 documented activity across ~4,000 human genes, with fibroblast expression patterns shifting closer to younger cells
Regulatory & Legal Status Tesamorelin holds a regulatory status no other peptide in this comparison shares it is FDA-approved, but only for one specific indication: reducing excess visceral abdominal fat in HIV patients with lipodystrophy, administered under a licensed prescription as Egrifta
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