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The mechanism relevant to tendon healing centers on VEGF pathway modulation and nitric oxide system regulation, both of which support the angiogenic and inflammatory phases of tissue repair
The tenosynovium (tendon sheath) benefits from enhanced healing while the tendons themselves undergo repair and strengthening
Work in the Linkermann laboratory was funded by the German Research Foundation SFB-TRR205, SFB-TRR 127, SPP2306 and a Heisenberg professorship to A.L., project number 324141047, and the international research training group (IRTG/GRK) 2251 and 3019
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