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7-9 GLP-1 signaling has been shown to promote microglia-mediated expression of neurotrophic factors, such as brain-derived neurotrophic factor and nerve growth factor, to promote neuronal survival and inhibit stress pathways in neurodegenerative conditions

4 Results like these are encouraging, but the trial was small

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OP0017 BCMA CD19 compound chimeric antigen receptor T cells (cCAR) provides complete humoral reset, eliminates all elevated autoantibodies, improves symptoms and renal function in lupus nephritis (LN) patients