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They can also cause a rapid rise in blood sugar levels, which can undermine weight loss effects as well as Wegovys beneficial cardiovascular effects

Side effects that are pronounced during the first months of treatment often diminish as receptors downregulate and the body finds a new equilibrium

These appointments can provide valuable opportunities to assess weight loss goals, discuss any challenges faced, and evaluate the effectiveness of the medication

Some medications may interact with topiramate (such as oral contraceptives, which may be less effective particularly at doses 200 mg/day) or affect the tolerability of semaglutide