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However, the use of antioxidants in cancer therapy is complex and context-dependent, as ROS also play essential roles in normal cellular signaling and immune responses

Separation was achieved on a Waters Premier BEH Z-HILIC column (1.7 m, 2.1 150 mm) using 20 mM ammonium bicarbonate solution with 0.1% ammonium hydroxide and 0.1% InfinityLab deactivator as mobile phase A and H 2 O/ACN (1:9 ratio) with 0.1% InfinityLab deactivator as mobile phase B