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How much of it is just due to the low insulin versus other things that are happening with fasting

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Because TG2 activity is highly associated with cellular redox status and alterations in the bidirectional flux of cellular thiol modulate TG2 activity, regulation of thiol flux in cells probably affects the TG2-mediated aggregation of the GST tag and its interaction with cellular proteins

Glutathione-related antioxidant defense system in elderly patients treated for hypertension