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Biotin is often given to improve hair and skin health or to address deficiencies, which can cause hair thinning and other issues
87 A related principle may also operate in inflammatory tissue niches, where oxidized lipids, often associated with lipoprotein particles such as low-density lipoprotein (LDL), are cleared by resident immune cells, thereby modulating local ferroptotic thresholds and potentially influencing the permissiveness of propagation
Heart failure or significant cardiac conditions: IV fluid volume can increase cardiac workload
Global sensitivity analysis (GSA) GSA is a very useful tool to investigate the qualitative behavior of a mathematical model, and we have applied it previously to a model for cone photoreceptor metabolism 62,63
