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The interaction table varies the oversight level by drug class: standard monitoring for conventional DMARDs, individualized case-by-case review for IL-6 inhibitors, and coordinated evaluation for JAK inhibitors

TB-4: repair-cell movement and tissue organization TB-4 is a naturally occurring 43-amino-acid peptide involved in cell movement and tissue repair

Certainty of evidence All primary and secondary outcomes were judged to have high certainty of evidence across all GRADE approach [11] domains, including risk of bias (D1), inconsistency (D2), indirectness (D3), imprecision (D4), publication bias (D5)

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