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This produces soluble factors which can induce demyelination or neurodegeneration either directly or indirectly through microglia activation (Lassmann, 2018)
A 2023 position statement from the Endocrine Society on GLP-1 receptor agonist therapy notes that "dose escalation intervals shorter than 4 weeks are associated with higher rates of treatment discontinuation and should be avoided in routine clinical practice." [11] That statement aligns with what SUSTAIN-7 and post-market real-world analyses have shown
These medicinesincluding semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)work by mimicking the action of the naturally occurring GLP-1 hormone
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