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Additionally, GIP receptor signaling activates PI3K, MAPK, and phospholipase A2 [103]
To boost glutathione levels, people may consider consuming foods rich in the amino acids required for its synthesis, such as cysteine-containing foods (e.g., garlic, onions, cruciferous vegetables) or take glutathione supplements (though the effectiveness of oral supplementation is debated)
SIN is a novel TrxR inhibitor that effectively sup-presses TrxR activity, inducing excessive ROS production in tumor cells, mediating oxidative stress responses, and promoting tumor cell apoptosis (125)