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Although the structure of the intestinal microbiota is very complex and the experimental design varies among studies, such as the different timing of HFD induction, distinctions in the duration of metformin treatment, and variations in mouse strains, but the impact of metformin on gut microbiota derived from these studies are nearly consistent

GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have become some of the most prescribed drugs in America

Magn Reson Med

Transfer of the associated accession numbers into the Kyoto Encyclopedia of Genes and Genomes (KEGG) for bioinformatic analysis demonstrated a multitude of metabolic alterations, as indicated by the fold enrichment of associated pathways represented within the dataset