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GLP-1 MODULATES LIPID METABOLISM GLP-1 Modulates fat synthesis in the liver GLP-1 modulates hepatic lipolysis GLP-1 modulates liver cholesterol metabolism GLP-1 modulates adiposynthetic and differentiation GLP-1 modulates fat browning Clinical application of GLP-1 in obesity Obesity is a major health problem worldwide
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Recording pipettes were filled with internal solution (pH 7.34, 290 mOsm) containing (in mM): 142 potassium gluconate, 10 HEPES, 1 EGTA, 2.5 MgCl 2 , 4 ATP-Mg, 0.3 GTP-Na and 10 Na 2 -phosphocreatine
For the HEDS assays, either GSH was varied between 100 M and 1.5 mM for ScGrx (or 250 M and 3.0 mM for PfGrx) at fixed concentrations of HEDS (0.18, 0.37, 0.55 and 0.74 mM) or HEDS was varied between 90 and 920 M at fixed concentrations of GSH (0.3, 0.5, 1 and 1.5 mM for ScGrx7 or 0.25, 0.5, 1 and 2 mM for PfGrx)
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