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NNMTs role is to transfer a methyl group to nicotinamide (vitamin B3), creating 1-methylnicotinamide a reaction that consumes cellular methyl donors and depletes nicotinamide adenine dinucleotide (NAD) stores
Heart Health: Helps to lower homocysteine levels, reducing the risk of heart disease
Similar results were obtained in vivo with enhanced reduction of patient xenograft tumor volume and the number of cells positive for proliferation markers
Most experienced researchers settle on 300-500mcg as the optimal daily dose
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