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Based on cross-trial data, CagriSema and tirzepatide produce nearly identical weight loss results, approximately 22 to 23% in non-diabetic populations with obesity
Hurley PJ et al
We previously examined GLP-1 dispensing and prescribing patterns immediately following the July 2025 CVS formulary change and found that switching from AOM tirzepatide increased more than 16-fold in July, with most patients transitioning to AOM semaglutide
82 Microstructural analyses showed trabecular thinning, increased separation and heterogeneitychanges most marked in postmenopausal subjects
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