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Supported by metabolic research but not yet by controlled trials specific to GLP-1 medications
High-dose intraperitoneal N-acetylcysteine (800 mg/kg) induced acute liver, kidney, and spleen damage in mice, leading to mortality
G6PD-deficient endothelial cells show reduced expression of endothelial NO synthase and decreased NO levels along with a reduction in GSH [11]
However, as with any topically applied active ingredient, reactions can occur, particularly in individuals with sensitive skin or pre-existing scalp conditions such as seborrhoeic dermatitis or psoriasis
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