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Growth retardation, general hypotonia, and loss of acquired neuromotor skills in the infants of mothers with cobalamin deficiency and the possible role of succinyl-CoA and glycine in the pathogenesis

UK guidance (MHRA and NICE) advises checking B12 levels in patients on metformin who develop symptoms of deficiency (anaemia, neuropathy) and considering periodic monitoring in those on long-term therapy

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Pregnant and breastfeeding individuals have increased requirements for many B vitamins, and indeed these vitamins are routinely included in prenatal supplements