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Patient education should address both the expected benefits and potential adverse effects of semaglutide, with particular emphasis on gastrointestinal symptoms that may be difficult to distinguish from autoimmune disease manifestations

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Budesonide treatment at doses of 0.51 g/kg significantly decreased DSS-induced edema, erythema, diarrhea, blood in stool, anorectal bleeding, and adhesions (Table 4), and these signs of inflammation were absent at budesonide doses of 10100 g/kg

Injectable semaglutide and tirzepatide compounds offer consistent drug exposure that oral formats cannot match