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Landmark clinical trials published since 2021, such as those investigating the effects of semaglutide and dulaglutide, have demonstrated a reduction in major adverse cardiovascular events (MACE) and a slowing of the progression of chronic kidney disease in patients with type 2 diabetes

From January to June 2025, AOM tirzepatide prescribing increased steadily (+0.09 percentage points per month)

Despite the availability of six FDA-approved anti-obesity medications (AOMs) for chronic weight management, current guidelines recommend waiting six months after behavioral therapy begins before adding pharmacological support

Documentation of symptom timing, severity, and associated features assists clinical decision-making and ensures appropriate care