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Full details of all analyses including an on-treatment approach using mixed models (a hypothetical estimand), the approach to analyze the supportive secondary and exploratory endpoints, details of the imputation model, and the multiple testing strategy will be provided in a statistical analysis plan that will be completed before the end of the trial, before unblinding of the results

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They also help contain or direct hot gases or flames if a cell goes into thermal runaway

In a meta-analysis published in the International Journal of Obesity in 2023 that looked at 5800 people, 78% lost 5% or more of their body weight