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And 40% of respondents are either very or extremely interested in losing weight this is a sentiment more popular among Gen Z (49%) and millennials (48%) than boomers (27%), and women (45%) than men (35%)

To validate whether C51 served as an additional CCW16 attachment site, we generated an RNF4 variant, in which C51 was mutated to serine as well as a double C51/91S mutant

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