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Jin J, Byun JK, Choi YK, Park KG
Food affects GLP-1 in two main ways: directly through nutrient sensing in the small intestine and indirectly by feeding gut bacteria in the colon so they produce short-chain fatty acids (SCFAs) that stimulate GLP-1 release
Melanotan-II is related to, but different from, afamelanotide, an approved drug used to treat the skin condition erythropoietic protoporphyria
Specifically, this paper delved into an overview of GLP-1s role at the physiological level as a modulator of the incretin effect, which is an important hormonal pathway whose dysregulation was explained to be implicated in the pathogenesis of T2DM
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