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Expected Weight Loss Timeline with Weekly Semaglutide Injections Meaningful weight loss typically becomes apparent within four to six weeks of starting semaglutide therapy at therapeutic doses, though some patients notice appetite suppression within days of their first injection

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The inflammation factor Looking at research done on people with obesity who take GLP-1 drugs, Henry and Pillsbury noticed that in addition to weight loss, patients saw improvements in immune function, including a decrease in inflammation