tirzepatide and vision changes NEJM Editorial Fellow Katerina Lin, MD, unpacks the science behind a study on Tirzepatide and Macular Degeneration: Current

By your mid-40s, you might need 200-300 fewer calories per day than you did in your 30s just to maintain the same weight

The PlexusDx Precision Peptide Genetic Test ($298) analyzes 14 pathways and 49 peptides to identify why semaglutide may not be your best fit, potentially pointing toward tirzepatide or dual-compound therapy as better options for your genetics

If nutritional deficiencies are identified, supplementation may be prescribed

However, important caveats exist: anyone with a personal or family history of medullary thyroid cancer or MEN2 syndrome (multiple endocrine neoplasia type 2) should not use semaglutide, as animal studies showed dose-dependent C-cell thyroid tumors