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Fair quality of methodology was considered in studies that enrolled only male subjects (population category) [14, 22, 25, 26, 28] or when blood sampling did not coincide with a steady state of an investigated drug [13,14,15,16,17, 19, 24]
As more people use semaglutide for diabetes and weight loss, future studies may provide clearer answers about its impact on mental health
Compound: Bacteriostatic water for research use
The European Medicines Agency's Pharmacovigilance Risk Assessment Committee (PRAC) reviewed the evidence in 2024 and concluded there is no causal link between GLP-1 receptor agonists and increased suicide risk, though continued monitoring is advised
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