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GLP-1 receptor agonists downregulate aberrant GnT-III expression in Alzheimers disease models through the Akt/GSK-3/-catenin signaling

Debated Unsettled Safety Issues Cancer Concerns about a possible connection between GLP-1 RAs and the development of neoplasms have spurred several investigations, especially on thyroid and pancreatic cancers due to a plausible mechanism and a large number of reports in the post-marketing phase [118, 128, 130]

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1 Therefore, T2D needs progressive therapeutic intensification targeting -cells, as described in worldwide diabetes-management guidelines