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Research published in the Obesity Reviews (PubMed PMID 27510423) confirmed in a meta-analysis that L-Carnitine supplementation produced statistically significant reductions in body weight, with effects most pronounced in overweight individuals and those with lower baseline carnitine levels

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Metabolic tracing studies further demonstrate that systemic NAD pools undergo inter-organ redistribution and are influenced by microbial metabolism and circulatory exchange [107, 108], indicating that NAD functions within a dynamic network rather than as a static intracellular reservoir [109]

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