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Additionally, a rise in IGF-1 levels by approximately 28% was observed, which may suggest enhanced functionality of the growth hormone-IGF-1 axis
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It says tirzepatide's metabolic changes, including improved insulin secretion, reduced glucagon signaling and weight loss, shift the baseline oxidative environment in cells, and that blanket antioxidant supplementation without baseline assessment may not match individual needs and could theoretically interfere with adaptive cellular responses to the medication
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