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The observed results always depend on the model used, the experimental design, the concentrations employed, exposure times, and the selected analytical parameters

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In type 2 diabetic mice, Exendin-4 rapidly normalised blood glucose levels

While both belong to the class of GLP-1 receptor agonists (with tirzepatide also acting on GIP receptors), they have different pharmacokinetic profiles

There appears to be a genetic basis for resistance to their satiating effects

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