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A recent study evaluating gastric emptying with tirzepatide (Mounjaro) and oral contraceptives found that a single 5mg dose of tirzepatide was associated with an approximate 20% decrease in the amount of the oral contraceptive absorbed into the bloodstream
By lowering glucagon levels, semaglutide helps prevent blood sugar spikes, especially after meals
(STEP-1 trial)
While most people tolerate these medications well, there are some factors that can increase risk, like very high triglycerides or a history of pancreatic issues
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