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Step 4: If you experience severe vomiting or diarrhea, pause and call your healthcare professional

By selectively and potently inhibiting the ASIC1a and ASIC1b subtypes, with an IC 50 between 11 and 300 nM, mambalgin-1 showed a potent analgesic effect, while mambalgin-2 is a powerful and reversible inhibitor of ASIC1a (Diochot et al., 2012)

The definition of injection site reactions in clinical trials typically includes pain, erythema, pruritus, and other local symptoms that patients report to investigators

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