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Archived from the original on 18 May 2019

MECHANISMS OF ACTION OF GLP-1 RAs AND MULTI-AGONIST THERAPIES Incretin-based therapies leverage the physiological roles of gut-derived peptide hormones, principally glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptor (GCG) to address the multifaceted pathophysiology of MASLD

It also appeared that BPC-157 may have regulated the phosphorylation level of extracellular signal-regulated kinases 1 and 2 (ERK1/2) and their downstream targets, including c-Fos, c-Jun, and Egr-1

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