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doi: 10.1227/NEU.0000000000000577

DSIP Peptide At a Glance Why People Are Talking About DSIP for Opioid Dependence When someone comes off opioids, a few things tend to hit hard: Severe insomnia Anxiety and restlessness Dysregulated stress response Physical discomfort DSIP gets attention because its believed to: Promote deeper, more restorative sleep Help regulate stress hormones Potentially reduce withdrawal-related discomfort Some early research has explored DSIPs effects on withdrawal symptoms, including in opioid-related contexts

76 , 24452450 (2010) DOnofrio, A

And over time, weight regain becomes more likely